Forskolin is a diterpene derived from the root of Coleus forskohlii. It’s used for various states, including cancer, obesity, glaucoma, asthma, and heart failure. Forskolin was demonstrated in animal studies to boost the activation of adenylate cyclase and increase intracellular concentrations of cyclic adenosine monophosphate (cAMP). Little clinical trials did suggest forskolin can benefit fat guys in weight management. Forskolin eye drops may reduce intra ocular pressure and oral forskolin capsules help reduce asthma attacks. When administered intravenously or inhaled, Forskolin has bronchodilation effect. Other studies demonstrated forskolin to get cardiovascular benefits because of its inotropic, antiinflammatory and antiplatelet properties. One clinical study found intraarterial forskolin daropate to be an effective treatment for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. Treatment of uropathogenic E.coli contaminated mice with forskolin resulted in reduced number of bacteria via cyclic AMP-regulated exocytosis. The anticancer effects of forskolin and its derivatives also have been analyzed in vitro and in animals. Forskolin, when applied on the skin of mice, can stimulate the production of melanin in the absence of ultraviolet light. It’s been proposed to be used in sunless tanning lotions to decrease the chance of skin cancer by reducing exposure to sun. In an in vitro study, an infusion of forskolin was found to significantly reduce viral production in human lymphoid CEM-GFP cells infected with human immunodeficiency virus (HIV-1NL4). These effects have not yet been confirmed in human studies. Patients using anticoagulants and antihypertensive drugs should use forskolin with caution. Instances of acute poisoning after the eating of Coleus forskohlii merchandises, possibly from contaminants, have been reported in Europe.
I somehow was linked this video on youtube and the guy in it is so hot. Sorry for making this a bit awkward but hey, at least I can delete this once the site is back up to 100% functionality!
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After a huge loss of our database, and the last two tarballs that were saved for backups were corrupted, we’re finally back online. We are going to be adding contently slowly, but surely! We have some very exciting things happening, and will share them as soon as we can! If you have any questions or comments, or would like to reach out to us, we have our contact form up.